Millar questioned not only the substance -- human chorionic gonadotropin, a female fertility drug -- but how Ramirez allowed it into his body and the doctor who reportedly subscribed it to him.

"Hey, it's not rocket science, you test positive, you are responsible," said Millar, who pulled out a container of pills from his locker to show reporters he takes supplements, but knows whether any of them fall on the banned list or not.

"I don't have any of those things going on inside of me," Jays manager Cito Gaston said when asked if, as a manager and a veteran of five decades in the game, he was shocked or saddened by the revelation. "Manny plays for the Dodgers, he's over in the other league now, so it doesn't bother me one way or another. But it is sad for me because I'm a fan of Manny the hitter. When you have a runner on second, he's the guy you'd love to have up at the plate. It's also sad for me because of what it might mean to him now and in the future -- it may keep him out of the hall of fame."

"He was a great hitter, but not inspirational," Millar said. "Probably one of the best pure hitters the game has ever seen. He has the sweetest right-handed swing in our generation for sure, and maybe the best the game has seen."